Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

惊险、欢快与不安交替进行,乔纳森·格雷泽导演的非凡之处在于让色情电影难得的实现了幻想与现实的融合。
Supporting Actor in a Limited Series or Movie: Sterling K. Brown, “The People v. O. J. Simpson: American Crime Story”
On the sales front, General Motors and Ford F -0.13% lost market share to Chrysler, which leveraged its Jeep brand to previously unimagined heights – and then, metaphorically left its heritage behind when it established legal domicile in the Netherlands and changed its name to FCA US LLC.
如果计划生育法修正草案在星期日被中国最高立法机关批准,全面二孩政策的实施将不再会有任何法律障碍。
Mayweather vs McGregor Fight
房地产经纪公司莱坊(Knight Frank)的数据显示,今年第一季度,香港豪宅租金同比下跌5.2%,跌幅超过内罗毕以外的任何其他城市。就在去年9月价格下跌之后,运动品牌阿迪达斯(Adidas)在香港租入了一间1.3万平方英尺的店铺,租金相比上一个租户、配饰品牌蔻驰(Coach)低了22%。
单词mortgage 联想记忆:
China has made huge progress in easing its residence and entry policies for foreigners since September 2015, which has helped attract more talent from overseas, as well as boost international exchanges and the economy, according to a ministry statement.
The number of moviegoers in 2016 reached 1.37 billion, an increase of nearly 8.9 percent year-on-year.
这就真相了,我同意。
China's online game revenue in 2008 was CNY20.8 billion, accounting for about 27% global share, ahead of South Korea at 21% and slightly behind the U.S. at 29%, according to an earlier report by Shanghai-based market research firm iResearch. The firm also predicted that China is likely to surpass the U.S. to become the world's largest by the end of 2009.
Below are a number of statements that people often use to describe themselves.
Piggyback riders are designed especially for small children and toddlers, to lessen the parents’ struggles.
4. Mark Turner Quartet “Lathe of Heaven” (ECM) On his first proper album as a leader in 13 years, the tenor saxophonist Mark Turner favors slithery interplay with the trumpeter Avishai Cohen, and finds new purpose in post-bop protocols. There’s dry intrigue in his compositions, and supple exactitude in his rhythm team: Joe Martin on bass, Marcus Gilmore on drums.
埃尔·南德斯
Whatever she needs to invoke the weightlessness of life in our new not-normal, she takes. "Is it the end of an era? Is it the end of America?" she intones in "When the World Was at War We Kept Dancing." "No, it's only the beginning."
一项由中国职业介绍机构智联招聘(Zhaopin)对1.15万名员工开展的调查发现,2016年底有50.9%的员工没有拿到年终奖。还有9.6%的员工则被告知年终奖会推迟至春节假期后发放。
"这是波多黎各的历史时刻",50岁的何塞·达维拉,他从力挺罗塞略的政党上挥舞大旗一边说着。"总督是我们岛上的希望,也是受苦的人民的希望"。
But we are going to get a taste of the new world order when the WTO’s members gather for its biennial ministerial in Buenos Aires in December. It’s unclear, as always, if the WTO will be able to deliver anything of substance. But the real test lies in not having the US leading the way in discussions for the first time in the WTO’s life. Will China step in? The EU? And will India be as minded to block any deal as it has been in the past?
Rouslan Krechetnikov和Hans Mayer对液体的溅出现象进行了研究。他们考察的课题是:人们在端着咖啡杯走动时咖啡的溅出情况,给你个提示吧,在你走到第七步至第十步之间,咖啡最容易溅出。
桑迪已经造成大规模损害,很可能带来更多灾害。
Mr Koepke argues, however, that the role of US interest rates in provoking EM crises has not been fully understood. He presents evidence that the probability of EM crises is substantially higher during a conjunction of three conditions: during a Fed tightening cycle, when the federal funds rate is above its natural rate (the rate that leads actual output to converge to potential output), and when market participants are surprised by signals that the Fed will tighten policy faster than previously expected.
Capsized ship righted
In a working paper published on Tuesday, Robin Koepke, economist at the Institute of International Finance, an industry group, argues that investors, EM policymakers and the Fed itself have neglected the role of US interest rates in provoking currency, banking and debt crises in the emerging world.
报告还发现,在当地政府的努力下,北京、深圳、广州、上海等一线城市的交通拥堵状况没有恶化。


China's best performances by subject this year come from Tsinghua University, with three top-10 places, and Peking University, with two top-10 places. Tsinghua University finishes eighth in both Architecture/Built Environment and in Engineering (Civil and Structural). Tsinghua comes in 10th place in the world's Materials Science subject rankings.
星期三,美国财政部长杰克·卢宣布了这一计划。他说,财政部将发起一个名为“新10元”的社交媒体运动,并将举行一系列公民会议,征集人们的想法,以确定在新版10美元钞票上印哪位女性的画像。
This is going to be one very interesting movie that shows the relationship between Captain America and Iron Man, who've always had trouble trusting each other.


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

李说,今年有好几个服务于老龄化人口金融和医疗需求的工作挤进了前10名,包括听力矫治专家、理财规划师和理疗师。
Apple CEO Steve Jobs poses with the new iPhone 4 during the Apple Worldwide Developers Conference in San Francisco, California in this June 7, 2010
根据国内领先的求职平台前程无忧近日发布的一份关于2016年应届毕业生的研究报告显示,52.11%的高校毕业生已找到工作或自主创业。
库迪斯和沃斯在孜孜不倦分析荷兰金融记录的过程中得出了结论,悲观者和乐观者之间真正的区别在于他们是否亲身经历过这样的痛苦过程。库迪斯认为,可以类比的是那些经历过大萧条的人们的行为:这些人在大萧条梦魇过去后的几十年里,一直回避金融风险。

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

只有公民,而他们的选择不仅可能、而且必然会改变。

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

质检总局副局长梅克保说道:“各级质量监督部门必须加强质量监督、继续打击违法行为,从而提高产品质量、保护消费者的权利。”
immunity

Still relevant
前“世界小姐”朴雅卡·乔普拉位列2015世界美女榜第九。她是一名印度演员兼歌手,是宝莱坞片酬最高的女演员之一,也是印度最受欢迎、知名度最高的名人之一。她获得过无数荣誉,包括印度国家电影奖的最佳女演员奖项,以及印度电影观众奖的四项大奖。
re再次+form形状→再形成→改革,改造
谷歌2017搜索排名靠前的包括马特·劳尔和飓风厄玛。搜索巨头公布了它今年的年度搜索结果榜单,内容主要是在全球各类行业中谷歌搜索排名靠前的几位。
Courtney Weaver
伦敦商学院课程的一个主要优势是学员来自地域广泛的不同国家。其2015年MBA课程学员的90%来自海外,来自大约60个不同国家。

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


东莞租房提取公积金每月上限增至1800元


References

1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017. www.prnewswire.com/news-releases/fifth-annual-pulse-of-online-health-survey-finds-66-of-americans-eager-to-leverage-digital-tools-to-manage-personal-health-300039986.html.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


No.2: Another Reason for Staying in Bed
We will make solid efforts to pursue the Belt and Road Initiative.
STEP 4: REMIND EVERYONE about what an "idiot" or "moron" they are
But top managers at companies in the fields of scientific research and technology services saw their pay decrease by 4.2%.
But even in a bad economy some jobs are just not worth it. Are there any telltale signs you should be looking for when trying to decide if you throw in the towel? Here are ten signs to look for to determine if it's time to find a new job:
The U.S. Congress and the media will go berserk when Goldman announces the size of its 2009 bonus pool. But the outrage will be brief and of little lasting consequence. The 'hate Goldman Sachs' story has been running just too long.
人的身体是十分脆弱的,有些娇弱的器官一旦破坏就永远难以复原。幸运的是,世界各地的研究人员都在研究能替代我们身体部位的生化机械器官。
Another positive of the scheme is that it encourages professional flexibility, preparing the young for the career zigging and zagging that might be necessary in the modern world of work.
In local currency terms exports managed slight growth of 0.6 per cent last month, besting expectations of 0.1 per cent contraction but still down substantially from growth of 5.9 per cent in November. Imports grew 10.8 per cent in renminbi terms, more than double the expected 4.8 per cent but down 2.2 percentage points from the month prior.
在经过了漫长的海选和五天紧张的半决赛之后,11位候选选手中其中一位成为了第八季英国达人秀2014年的冠军。

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



Above is the information needed to cite this article in your paper or presentation. The International Committee of Medical Journal Editors (ICMJE) recommends the following citation style, which is the now nearly universally accepted citation style for scientific papers:
Halpern SD, Ubel PA, Caplan AL, Marion DW, Palmer AM, Schiding JK, et al. Solid-organ transplantation in HIV-infected patients. N Engl J Med. 2002;347:284-7.

About the ICMJE and citation styles

The ICMJE is small group of editors of general medical journals who first met informally in Vancouver, British Columbia, in 1978 to establish guidelines for the format of manuscripts submitted to their journals. The group became known as the Vancouver Group. Its requirements for manuscripts, including formats for bibliographic references developed by the U.S. National Library of Medicine (NLM), were first published in 1979. The Vancouver Group expanded and evolved into the International Committee of Medical Journal Editors (ICMJE), which meets annually. The ICMJE created the adj. 相同的,同一的 to help authors and editors create and distribute accurate, clear, easily accessible reports of biomedical studies.

开发商:Frontier、Microsoft Studios
A sub-index tracking activity at larger enterprises softened 0.7 points to 53.1, while mid-sized companies fell 1.3 points to 49.9, indicating slight contraction. That for smaller manufacturers fell 0.4 points to 49, indicating worsening contraction.
待售房产:一栋带有四间卧室与四间半浴室的希腊复兴式房屋
但是,在秀台上和零售店里,那种情感上的认同消失了。那么,我们还剩下什么?

在这场充满政治色彩的颁奖典礼——唐纳德?特朗普(Donald Trump)屡次成为主持人吉米?基梅尔(Jimmy Kimmel)打趣的对象——的末尾,沃伦?比蒂(Warren Beatty)和费?唐纳薇(Faye Dunaway)宣布《爱乐之城》赢得此奖项。然而,就在这部达米安?沙泽勒(Damien Chazelle)编导的现代音乐片的制作人员和演员登上舞台、激动地发表致谢演说时,他们却被告知《月光男孩》才是真正的获奖者。

  • Only the first three authors are listed, followed by "et al."
  • 2015年年度家居“大片”榜单出炉!
  • 宁沪等地楼市库存降了又升 开发商仍叹压力大


该报告还指出,那些在经济衰退期间不得已裁减支持型岗位的公司,也会“补充新人,以帮助各部门提高效率,提升生产力水平。”对于求职者而言,这一趋势无疑预示着一个美好的新年。
来源:前十网

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